Is this in a e-revo? or converted?
Because if its in an e-revo, I made a chart that might help;
(short answer is yes, if you mount the motor in the low-cg spot)
This is used in an e-revo with a tekno neu and RCM pinion gears...
unfortunatly, I dont have a 22t, but I got the 20t pinion to mesh with a spur as small as 53T...using the low-cg mounting holes;