The powerpoles are a great connector. To use them on 12 (and some 14) gauge wire you may have to force the metal openning a little wider than stock. I've spent the last 2 months swapping my deans for powerpoles, and I don't see myself going back. I have about 40 deans laying in my toolbox now :)
The powerpoles aren't gender-specific and they allow you to wire in series without a harness.
I don't solder my powerpoles due to a message I read from an Anderson (makers of powerpoles) rep. He said that the crimped connection is inherently better because all of the current goes through the twisted copper strands right to the connector with no solder in the way. Both the wire and the connector have less resistance than solder, so it's not a bad idea to avoid solder when possible.
I don't take his word as gospel, but I can say that I haven't had a single problem with the powerpoles and I'm a very pleased customer.
It also helps that they are about half the cost of deans, too. :)
Lastly, I know there are questions regarding how many amps the connectors can handle, but the only information I have been able to find (that seams at all reliable) shows both deans and powerpoles at 30 amps, so I'm not concerned there. My own experience has shown that they have zero problems in real use.
http://www.hobbyhorse.com/connectors.shtml
Anderson clearly states the amps on their products, but I can't find information directly from wsdeans regarding the ultra connector's amps.