Revo conversion

I literally just found the gearing calculator,and I have a question, the only batts I have right now are some rc-monster 2500mah 5s that I plan to run as a 5000mah pack but I plan to buy some 4s and 6s also. With a wide ratio 2nd gear and a stock 38 tooth spur if I ran a 22 tooth pinion I get a nice medium of about 44mph on 5s,50mph on 6s and 34mph on 4s,would it be ok to run this way,or will I have to regear for every set of batterys I run to keep temps and current draw down?--Josh