mmm 2200kv combo ok to run on 2s and 3s

mmm 2200kv combo ok to run on 2s and 3s is it ok to run around on 2s and 3s lipos sometimes or will it damage motor or esc? just sometimes my nephew come and wants to have a go so i just run 1 batterie pack so its not so fast will this be ok? i have 2x5000mh2s1p lipos at 20c and 2x5000mh 3s1p lipos at 20c when i bash and race i use them in series to make 4s/5s and 6s most of the time it runs on 4s and 5s