According to CC no. Your settings look fine to me and the MMM was built to run 6 pole as well. I was very pleased with how smooth my MMM ran the Align 600XL I had.
Well, a 4 pole motor will work the esc twice as hard as a 2 pole motor. So a 6 pole motor will work the esc harder still than a 4 pole. The fets are rated for a certain number of cycles, so it may last longer with a 2 pole motor. However as long as the temps are good, the esc should last just fine with either motor.