I'm installing my win7 (MSDNAA) right now on my desktop-pc.
The win7 RC ran fine, so why should the final version be worse.
And since it's heavily based on Vista it's not an entirely new OS, so there shouldn't be any bugs as bad as there were in the XP and Vista relase versions.
Have just replaced the wife's PC (7yrs old) with a XPS8000 studio. Came with 64bit ver of Vista, she seems to like it, but I see what you mean about obtrusiveness - get asked to confirm everything you do. It came with the Win7 upgrade offer and I've already registered.
Its time to replace my 2 business laptops and I may wait for Win 7 SP1 unless I start having issues with either. Friend dnloaded the beta ver of Win7 and really likes it, but he jumped from XP and doesn't have any feeling for how diff/better it is relative to Vista.