It'll run great. I've run a Vortex 5.5 with a MM before the latest firmware upgrade and it worked great. I can only imagine that with the newest firmware upgrade, it'll be even smoother.
I ran a Novak hv4.5 on a MM with 2S in a crt.5 till my Medusa came. Only had to run it for a couple days but had no issues. Iactually thought about keeping it in there but didn't want to cut the sensor cable and I wanted to use a bigger pinion than 11t, 5000kv is a bit much even on 2S, at least for my liking.