Another question...volts and esc

[speed demon]

I went from a 3S with 3500kv to a 4S 2200 and love the longer run times and cooler temps. So my more is better idea is coming out here..what if I go to a 1600kv and 6S on a mod MM? Does volts kill an esc or amps? The motor is rated a decent amount less amps(17) so will this combo work? Also my MM didn't even break 100 with cool night air and a 40mm fan on 4S. Thanks again guys.